

On 14 October 2011, the authors issued a partial retraction of their paper that touched on issues with some of their figures.

On 1 July 2011, Science’s editors issued a “statement of concern” about the paper. Numerous attempts failed to replicate the study, and the research itself came under increasing scrutiny for sloppy methods and its reliance on misleading or manufactured figures. However, as with so many other potentially groundbreaking studies, nobody - including many of the same researchers involved with the original study - was able to replicate its results. The paper received substantial international coverage. Her team alleged to have demonstrated an association between a newly discovered retrovirus called "xenotropic murine leukemia virus-related virus" (XMRV) and the poorly understood condition known as Chronic Fatigue Syndrome (CFS), suggesting a potential viral cause for CFS.

In 2009, biologist Judy Mikovits, who was then the research director of the Chronic Fatigue Syndrome-focused Whittemore Peterson Institute (WPI), published a paper on what she and many others thought to be a major scientific breakthrough in the prestigious journal Science.
